|
|
cotinine <=> cotinine_methonium_ion
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-167
|
|
|
|
UDP-glucuronate + trans-3''-hydroxycotinine <=> trans-3-hydroxycotinine-glucuronide + UDP + H+
|
2.4.1.17
glucuronosyltransferase
|
–
|
| |
MetaCyc:
RXN66-162
|
|
|
|
nicotine-Delta1''5''-iminium_ion + O2 + H2O <=> H+ + cotinine + H2O2
|
1.2.3
|
–
|
| |
MetaCyc:
RXN66-62
|
|
|
|
norcotinine <=> 4-oxo-4-(3-pyridyl)-butanamide
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-104
|
|
|
|
gamma-Hydroxy-3-pyridinebutanoate + acceptor <=> 4-oxo-4-(pyridin-3-yl)butanoate + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN66-141
|
|
|
|
N''-hydroxymethyl-norcotinine + reduced_flavoproteins + O2 <=> norcotinine + oxidized_flavoproteins + H2O
|
1.14.14
|
–
|
| |
MetaCyc:
RXN66-170
|
|
|
|
cotinine <=> cotinine_N-oxide
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-166
|
|
|
|
4-oxo-4-(3-pyridyl)-N-methylbutanamide <=> 4-oxo-4-(pyridin-3-yl)butanoate
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-165
|
|
|
|
cotinine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 5''-hydroxycotinine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
| |
MetaCyc:
RXN66-163
|
|
|
|
4-oxo-4-(3-pyridyl)-butanamide <=> 4-oxo-4-(pyridin-3-yl)butanoate
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-105
|
|
|
|
UDP-glucuronate + cotinine <=> cotinine-glucuronide + UDP
|
2.4.1.17
glucuronosyltransferase
|
–
|
| |
MetaCyc:
RXN66-168
|
|
|
|
Nicotine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> nicotine-Delta1''5''-iminium_ion + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.19
|
–
|
| |
MetaCyc:
RXN66-61
|
|
|
|
cotinine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> N''-hydroxymethyl-norcotinine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
| |
MetaCyc:
RXN66-169
|
|
|
|
gamma-Hydroxy-3-pyridinebutanoate <=> 4-(3-pyridyl)-3-butenoate
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-142
|
|
|
|
cotinine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> trans-3''-hydroxycotinine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
| |
MetaCyc:
RXN66-161
|
|
|
|
5''-hydroxycotinine <=> 4-oxo-4-(3-pyridyl)-N-methylbutanamide
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-164
|
|
|
|
4-(3-pyridyl)-butanoate + acceptor <=> 4-(3-pyridyl)-3-butenoate + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN66-144
|
|
|
|
4-(3-pyridyl)-butanoate <=> 3-pyridylacetate
|
not assigned
|
–
|
| |
MetaCyc:
RXN66-145
|
|
